Protein, Muscle, and Why the Old Rules Changed
Dr. Helena Brandt, Clinical Lead, Metabolic MedicineMay 30, 202611 min
Nutrition advice tends to be written for an average person who does not exist, and almost never for someone in the middle of a hormonal transition. This lecture is narrower and more useful: what the evidence says about protein and muscle in midlife, and why the answer has shifted from the guidance many of us grew up with.
The body becomes less efficient at building muscle with age, a phenomenon researchers call anabolic resistance. In practical terms, the amount of protein that once maintained lean mass no longer quite does, and the threshold to stimulate muscle protein synthesis rises. This is why blanket recommendations set decades ago tend to fall short for people in this stage, and why distribution across the day matters as much as the daily total.
Muscle is not a matter of appearance. It is metabolic infrastructure and the single best predictor we have of how mobile and independent you will be in later decades. Defending it is one of the highest-leverage things you can do now, and the window in which it is easiest to do is the one most people are in when they first come to us.
We translate this into specifics with your physician rather than a generic chart, because the right target depends on your markers, your composition, and what else is on your plan. What this lecture gives you is the reasoning behind those specifics, so the recommendations you receive read as deliberate rather than arbitrary.